Exam Name: Clinical Trials Programming Using SAS 9.4
Certification Provider: SASInstitute
Corresponding Certification: SAS Clinical Trials Programming
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Updated: Aug 11, 2026
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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Macro Programming for Clinical Trials | 15% | - Macro variables and parameters - Debugging macros - Create and call macros |
| Topic 2: Clinical Trials Process | 5% | - Derive programming requirements from protocol and CRF - Clinical trial lifecycle and protocol |
| Topic 3: Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
| Topic 4: Clinical Trials Data Structures | 10% | - CDISC standards: SDTM, ADaM - Clinical domain structures - Define.xml and dataset specifications |
| Topic 5: Validate Clinical Trial Data Reporting | 20% | - Use PROC COMPARE and log review - Programming validation techniques - Validation principles |
| Topic 6: Transform or Summarize Clinical Trials Data | 15% | - Aggregation and transposition - Derive variables and study days - Data step manipulation |
| Topic 7: Manage Clinical Trials Data | 5% | - Clean, merge, and subset data - Access and explore clinical datasets - Use SQL and dictionary tables |
| Topic 8: Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Topic 9: Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
1. Vital Signs are a component of which SDTM class?
A) Special Purpose
B) Interventions
C) Findings
D) Events
2. The following SAS program is submitted:
What is the value of the second variable in the data set WORK.DIGESTL?
A) divertic
B) a missing value
C) No variables are created.
D) diverticulosis
3. A report that you are working on will require the following header lines:
Which code adds the second line of the header "Adverse Events"?
A) title2 'Adverse Events';
B) header2 'Adverse Events';
C) header2 = 'Adverse Events';
D) title2 = 'Adverse Events';
4. The following SAS program is submitted.
What result is displayed for the variable COUNT?
A) 3
B) 2
C) 1
D) 4
5. A Statistical Analysis Plan defines study day as the number of days between the visit date and the date of randomization plus one day.
The following SAS program is submitted using a macro from the project's library:
How is the STUDYDAY macro defined?
A) %MACRO studyday(rand, visit);
&visit. ?&rand. + 1
%MEND studyday;
B) %MACRO studyday(visit=, rand=);
&visit. ?&rand. + 1
%MEND studyday;
C) %MACRO studyday(rand, visit);
&vdt. ?&rdt. + 1
%MEND studyday;
D) %MACRO studyday(rand=, visit=);
&vdt. ?&rdt. + 1
%MEND studyday;
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: A | Question # 3 Answer: A | Question # 4 Answer: A | Question # 5 Answer: A |
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